The 2025 GCIG Spring Meeting in Chicago gathered over 170 delegates from all 33 member groups, focusing on pragmatic trials – cost-effective, patient-centred studies applicable in real-world clinical practice, including low-resource settings. The meeting featured impactful plenary sessions, pre-recorded lectures, and interactive brainstorming in disease-specific groups. Discussions covered topics such as:

• Involving patients from trial design to result dissemination
• Reducing toxicity without compromising efficacy
• Innovative approaches like synthetic control arms, dose de-escalation, fertility-sparing approaches, AI modelling, and decentralized trials
• Designing inclusive protocols with broader eligibility criteria
• New proposals in ovarian, endometrial, cervical, and rare tumours, as well as symptom benefit research

The brainstorming sessions generated 33 trial concepts, of which 15 were discussed in detail. Early Career Investigators played an active role, contributing ideas and collaborating internationally.

CEEGOG was represented by Dr. Zoltán Novák from the National Cancer Institute, Budapest. Our sincere thanks to Dr. Novák for representing our group at this important international meeting.

The next GCIG Autumn Meeting will be held on October 15–16, 2025, in Berlin, Germany.