We sincerely thank all participating institutions for their valuable contribution to the REGYS project, a retrospective study focused on rare gynecological sarcomas, which has so far resulted in five publications — three in Q1 journals and two in Q2 journals.
In addition, at least two further publications, focusing on MTAP deletion and on an mRNA expression profile classifier, are currently in preparation and will also be co-authored by all participating institutions.
Given the uniqueness of the collected samples, we are now preparing a follow-up project: REGYS-2. Details of the new REGYS-2 project will be shared soon, along with an invitation to participate. We sincerely hope for your continued collaboration.
Publications co-authored by all participating institutions:
1. Dundr P, et al. The Rare Gynecologic Sarcoma Study: Molecular and Clinicopathologic Results of A Project on 379 Uterine Sarcomas. Lab Invest. 2025 May;105(5):104092. doi: 10.1016/j.labinv.2025.104092
2. Hojný J, et al. Decoding the Molecular Landscape of 262 Uterine Sarcomas: RNA-Seq Clustering of ESS, UTROSCT, and UUS with Prognostic Insights. Lab Invest. 2025 May 24:104198. doi: 10.1016/j.labinv.2025.104198
3. Flídrová M, et al. Immunohistochemical analysis of 147 cases of low-grade endometrial stromal sarcoma: refining the immunohistochemical profile of LG-ESS on a large, molecularly confirmed series. Virchows Arch. 2025 Jan 21. doi: 10.1007/s00428-025-04026-4
Publications co-authored by contributing institutions only:
1. Dundr P, et al. Uterine sarcoma with KAT6B/A::KANSL1 fusion: a molecular and clinicopathological study on 9 cases. Virchows Arch. 2025 Mar;486(3):551-562. doi: 10.1007/s00428-024-03994-3
2. Flídrová M, et al. Unraveling the Molecular Landscape of Uterine Tumor Resembling Ovarian Sex Cord Tumor: Insights From A Clinicopathological, Morphologic, Immunohistochemical, and Molecular Analysis of 35 Cases. Mod Pathol. 2024 Dec;37(12):100611. doi: 10.1016/j.modpat.2024.100611
We look forward to continuing this important collaboration in the upcoming REGYS-2 project.