We would like to update you on the change of the CEEGOG residence. The proposal for the new place of residence was approved by all participants at the CEEGOG meeting in December 2016. Starting June, 2017, the Association resides in the city of Prague, Na Folimance 2155/15, Praha 2 – Vinohrady.

CEEGOG was represented by Roman Kocian in the meeting. Participants were welcomed by Prof. Ignace Vergote, Cristiana Sessa, Antonio Casado.
First, we discussed finalisation of umbrella trial synopsis for the following proposals: Alejandro Perez Fidalgo for recurrent endometrial cancer, Ros Glasspool on the Umbrella trial in platinum-refractory recurrent ovarian cancer, Nicole Concin on the Umbrella trial in Non-HRD recurrent ovarian cancer, Ronnie Shapira on the Umbrella trial in recurrent cervical cancer. Cristiana Sessa presented a new trial proposal on behalf of Viola Heinzelmann, President of Gyn working group of the SAKK, on a Phase II study with the MELK inhibitor in platinum resistant OvCa.
Second, funding strategies were discussed: e.g. if one trial can be realised in one country, other countries will try to join via self-organisation of funding within their country for this specific trial (e.g. by contacting the industry representative in the specific country or by applying for academic funding at national research bodies).
Third, the group reviewed the list of centres from each country for ENGOT Ph I/II network received from the national trial groups. The group suggested to abolish the limitation in the number of centres. The most important factor for a centre to be nominated should be experience in early Phase clinical trial performance in gynaecological malignancies and interest in doing so (feasibility questionnaire will be created and send out via ENGOT office to national trial groups).

Finally, there is an upcoming meeting with the industry in October 2017, where Ph1/Ph2 representatives will present their trial proposals. In relation to that, prof. Vergote spoke about the existing ENGOT rules on the cooperation with the industry

I am pleased to announce that CEEGOG will be represented in the third series of Gynaecological Cancer Academy workshops by Dr. Vít Weinberger from the University Hospital Brno (Czech Republic).

On March 3 - 4, 2017, a meeting of representatives of the twenty national trial groups was held in Spanish Valencia. CEEGOG was represented by its Chairman Prof. David Cibula and the administrative manager Mrs. Ivana Nohová.  

The Engot Admin meeting focused on EU regulations, the GCP amendment, trial budgeting, the ENGOT welcome package, the new ENGOT website, and on the summary of the strategic meeting held in Copenhagen in October 2016.
The main topic of the ENGOT assembly meeting involved trial activities and the status of collaboration as usual. The CEEGOG/ENGOT trials, i.e. the SENTIX trial and the ABRAX trial were disscussed, too. There is big interest to join the ABRAX study within ENGOT groups. It was agreed to send out the ABRAX protocol to all ENGOT groups.
The status of collaboration was presented and the integration of ENGOTgroups with less activity was also discussed. Altough being a relatively small and new group, CEEGOG is ranked among the active groups within ENGOT thanks to their Chairman´s activity and CEEGOG centers interest to participate in ENGOT trials. Moreover, Prof. David Cibula delivered again a presentation on the new project idea – SEDLIS 2020.
Other topics of discussion were as follows: rare tumors, how to manage competition with pharma and GOG, TR activity and tumor bank, finances and website, update on publication rules, GCA workshops, PhaseI/II trials and EVA privileged partnership.
For more information, you are welcome to contact the CEEGOG office.

Ovarian cancer study
Women with relapsed ovarian cancer can take part in SOLO3, a clinical study for ovarian cancer, supported by AstraZeneca, to help scientists find better treatments for this disease.  This page provides information about the SOLO3 clinical trial.
A clinical study of olaparib in women who:

Have previously been diagnosed and treated for ovarian cancer, peritoneal cancer, and/or fallopian tube cancer and their disease has come back. 

Have an inherited BRCA mutation. In case of an unknown BRCA status, patients are eligible to undergo BRCA testing even if they have not yet had recurrence or progression of disease >6 months (>/=183 days) after completion of their last platinum therapy. Note: The BRCA test is covered by the sponsor.

Have completed at least two courses of platinum-based chemotherapy, and finished the last course at least six months ago.  Platinum agents are carboplatin, cisplatin, and oxalaplatin
 
Have a tumor that has shrunk or disappeared following their last course of platinum-based chemotherapy
 
For information on SOLO3 participating study locations for referrals, please visit www.astrazenecaclinicaltrials.com and enter ‘SOLO3’ in the search box.
 

We would like to express our thanks for your participation in the CEEGOG meeting held in Prague on December 9, 2016. It is our pleasure to invite the 9 new centers for cooperation. Currently  CEEGOG is composed of 39 centres from 8 countries – the Czech Republic, Slovakia, Poland, Slovenia, Ukraine, Hungary, Belarus, Georgia.

We would like to invite CEEGOG members and friends to the CEEGOG meeting, which is going to be held  at the General University Hospital in Prague on Friday, December 9, 2016, from 9:30 am to 16:00 pm. Both CEEGOG members and CEEGOG friends are cordially invited to attend the meeting.

On October 6-7, 2016, a meeting of representatives of national trial groups was held at Scandic Stortoget Hotel in Malmö. CEEGOG was represented by its chairman Prof. David Cibula and the administrative manager Mrs. Ivana Nohová.

The Engot Admin meeting was focused on ENGOT documentation, risk based monitoring and budgeting a trial, monitoring network, on EU regulation and the GCP amendment.

The ENGOT Administrative meeting was followed by the ENGOT assembly meeting. The main topic involved trial activities and the status of collaboration. Group participation in ENGOT studies was also evaluated. Prof. David Cibula delivered a presentation on the ABRAX proposal of CEEGOG. It was decided that this could be an ENGOT tial. All groups showed interest in ABRAX. Other topics for discussion were as follows: privileged partnership application of EVA group (Brazil), new PGOG application, update of publication rules and reports from the ESGO council and working groups.

More information may be provided by the CEEGOG office on request.

The Gynaecological Cancer Academy (GCA), which is run by ENGOT, sets itself the goal of nurturing and developing the next generation of leaders in gynaecological oncology in order to ensure continuity and the transfer of knowledge and experience among members of the clinical trial community.

The 8th GCA workshop took place in Baveno on September 30, 2016. CEEGOG was represented by two physicians, namely Dr. Jaroslav Klát (University Hospital in Ostrava) and Dr. Roman Kocián (General University Hospital in Prague).

The main topic of the workshop was Non-ovarian cancer. The most important presentations of the training module are webcasted and available on ESGO eAcademy.

We would like to inform you that our Association  has endorsed the CEEGOG membership application of the Maribor center. We are pleased that CEEGOG has been expanding and currently includes centers from 4 countries - the Czech Republic, Slovakia, Poland and newly Slovenia.

It is our great pleasure to let you know that the protocol for the SENTIX trial (SENTinel lymph node in cervIX cancer) has been finished and the trial is now ready for new centers to join it and for new patients to be enrolled in.

SENTIX is a prospective observational international multicenter trial on sentinel lymph node biopsy in patients with early stage of cervical cancer. Our target is to enroll 300 patients and this could be achieved until the end of 2017.The trial chair is David Cibula, and the main investigator is Roman Kocian (General University Hospital in Prague, CZ). 

Since the SENTIX is the original CEEGOG trial it is our hope that the majority of CEEGOG centers will participate in it.

We are looking forward to our prospective mutual cooperation.  For futher information or if you have any queries, please do not hesitate to contact the CEEGOG office.

  1. Change of the CEEGOG residence, July 2016
  2. Gynaecological Cancer Academy (GCA), May 13 – 14, 2016
  3. HE4-FU-OVCA trial, April 2016
  4. CEEGOG meeting in Prague on April 20, 2016
  5. ENGOT meeting in Frankfurt, March 3 - 4, 2016
  6. ENGOT meeting in Nice, October 23, 2015
  7. Welcome new CEEGOG member
  8. ENGOT meeting in Frankfurt, February 18 - 19, 2015
  9. CEEGOG joins ENGOT
  10. CEEGOG founded